Diagnosing Iron Deficiency Anemia

  • Iron deficiency is common in patients with CRIa and a common cause of anemia1,2

  • In patients with anemia, an evaluation should be performed to determine the possible causes
    and contributing factors, including iron deficiency7

  • KDOQITM Guidelines recommend an initial laboratory assessment prior to initiation of therapy,
    including CBC, absolute reticulocyte count, serum ferritin, and TSAT

  • Diagnosing iron deficiency remains challenging because absolute iron levels may not reflect
    an underlying deficiency

  • While certain patients may not meet a strict definition for iron deficiency anemia (eg, serum ferritin
    <100 ng/mL and TSAT <20%), they still can mount a hemoglobin response to iron replacement therapy10
aChronic renal insufficiency (CRI) and chronic kidney disease (CKD) refer to the same condition; terminology differs among medical specialties.

CBC=complete blood count; KDOQI=National Kidney Foundation Kidney Disease Outcomes Quality Initiative;
TSAT=transferrin saturation.

KDOQI is a trademark of the National Kidney Foundation, Inc.

Now that you know about Diagnosing IDA, learn more about Absolute vs Functional IDA.

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